23

Cardiovascular diseases (CVD) are a leading cause of morbidity and mortality worldwide, placing significant pressure on global health systems. This paper explores the primary risk factors contributing to the development of CVD, focusing on genetic, environmental, and lifestyle factors. It highlights the complex interaction between these factors and their role in the pathogenesis and progression of cardiovascular diseases. Genetic predisposition, environmental pollution, and unhealthy lifestyle choices, such as poor diet, smoking, and physical inactivity, all play critical roles in the onset and progression of these diseases. By understanding these factors and their interplay, more effective prevention strategies and treatment options can be developed to combat the global burden of CVD.

  • Read count 23
  • Date of publication 05-04-2025
  • Main LanguageIngliz
  • Pages41-45
English

Cardiovascular diseases (CVD) are a leading cause of morbidity and mortality worldwide, placing significant pressure on global health systems. This paper explores the primary risk factors contributing to the development of CVD, focusing on genetic, environmental, and lifestyle factors. It highlights the complex interaction between these factors and their role in the pathogenesis and progression of cardiovascular diseases. Genetic predisposition, environmental pollution, and unhealthy lifestyle choices, such as poor diet, smoking, and physical inactivity, all play critical roles in the onset and progression of these diseases. By understanding these factors and their interplay, more effective prevention strategies and treatment options can be developed to combat the global burden of CVD.

Author name position Name of organisation
1 Yoldosheva S.G. ! Tashkent Medical Academy
2 Kasimova D.A. ! Tashkent Medical Academy
Name of reference
1 1.Gillespie, C., & Sunderlin, J. (2021). Genetic determinants of cardiovascular disease. Journal of Cardiology, 73(4), 450-460.2.Kannel, W. B., & Dawber, T. R. (2020). The Framingham Heart Study: A cardiovascular risk model. The New England Journal of Medicine, 382(3), 231-245.3.Liu, Y., Zhang, H., & Wang, L. (2019). The environmental impact on cardiovascular diseases: A review of pollution and its effects on heart health. Environmental Health Perspectives, 127(8), 860-875.4.Lopez, A. D., & Mathers, C. D. (2021). Global cardiovascular disease burden: Trends and determinants. Global Health Action, 14(1), 19-31.5.Marmot, M. G., & Stansfeld, S. (2003). Social determinants of cardiovascular disease: Evidence from longitudinal studies. Lancet, 362(9382), 1531-1537.6.Peters, A., & Dockery, D. W. (2018). Air pollution and cardiovascular disease: A review of the evidence. Environmental Health Perspectives, 126(9), 119-128.7.Tse, G., & Wang, H. (2020). Lifestyle factors and their impact on cardiovascular disease: Prevention and management. Journal of Clinical Medicine, 9(5), 1450-1461.8.WHO. (2023). Cardiovascular diseases (CVDs) Fact Sheet. World Health Organization. Retrieved from https://www.who.int/news-room/fact-sheets/detail/cardiovascular-diseases-(cvds).9.Zhao, L., & Zhang, Y. (2021). Impact of lifestyle changes on heart disease and prevention strategies. Chinese Journal of Preventive Medicine, 55(2), 112-119.10.Pérez, G., & Medina, C. (2017). The influence of genetics and family history on cardiovascular health. Heart and Vessels, 32(1), 33-39.
Waiting