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Drugs called diuretics are used to treat and control edematous and non-edematous medical disorders. One class of medications is diuretics. This exercise examines the uses, side effects, and indications of diuretics as a useful treatment for heart failure, hypertension, ascites, and other conditions as appropriate. In order to help members of the interprofessional team treat patients with heart failure and related conditions, this activity will highlight the mechanism of action, adverse event profile, and other important factors (such as off-label uses, dosing, pharmacodynamics, pharmacokinetics, monitoring, and pertinent interactions). Since diuretics are among the most widely given medications and, despite their effectiveness, are frequently usedto treat patients who are at a significant risk of problems, it is crucial to comprehend and value their pharmacokinetics and pharmacodynamics (see Keller and Hann's recent review). Despite the unique pharmacokinetic and pharmacodynamic characteristics ofthe available diuretic medications that influence response and the possibility of side effects, many clinicians use them in a stereotypical way, which decreases effectiveness and may increase side effects (a list of common diuretic side effects is provided). Although there are many applications for diuretics, this review will concentrate on their usage to treat edema and extracellular fluid (ECF) volume expansion; readers interested in learning more about how diuretics are used to treat kidney stones, hypertension, and other disorders are directed elsewhere

  • Read count 33
  • Date of publication 10-06-2025
  • Main LanguageIngliz
  • Pages 208-214
English

Drugs called diuretics are used to treat and control edematous and non-edematous medical disorders. One class of medications is diuretics. This exercise examines the uses, side effects, and indications of diuretics as a useful treatment for heart failure, hypertension, ascites, and other conditions as appropriate. In order to help members of the interprofessional team treat patients with heart failure and related conditions, this activity will highlight the mechanism of action, adverse event profile, and other important factors (such as off-label uses, dosing, pharmacodynamics, pharmacokinetics, monitoring, and pertinent interactions). Since diuretics are among the most widely given medications and, despite their effectiveness, are frequently usedto treat patients who are at a significant risk of problems, it is crucial to comprehend and value their pharmacokinetics and pharmacodynamics (see Keller and Hann's recent review). Despite the unique pharmacokinetic and pharmacodynamic characteristics ofthe available diuretic medications that influence response and the possibility of side effects, many clinicians use them in a stereotypical way, which decreases effectiveness and may increase side effects (a list of common diuretic side effects is provided). Although there are many applications for diuretics, this review will concentrate on their usage to treat edema and extracellular fluid (ECF) volume expansion; readers interested in learning more about how diuretics are used to treat kidney stones, hypertension, and other disorders are directed elsewhere

№ Author name position Name of organisation
1 Rashidov S.Z. Department of pharmacology Tashkent Medical Academy
2 Musaeva K.U. Department of pharmacology Tashkent Medical Academy
3 Shakhmurova M.A. Department of pharmacology Tashkent Medical Academy
4 Abdurazzoqov A.A. Department of pharmacology Tashkent Medical Academy
5 Shodmonova S. . Department of pharmacology Tashkent Medical Academy
№ Name of reference
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