Osteogenic sarcoma is one of the most common malignant bone tumors in pediatric patients, necessitating early and accurate diagnosis to improve treatment outcomes. A multimodal radiological approach, integrating conventional radiography, MRI, CT, and PET scans, offers a comprehensive diagnostic pathway. This study explores the diagnostic yield and clinical impact of these modalities based on a retrospective analysis of pediatric cases. Findings reveal that MRI and PET provide superior sensitivity for local and metastatic assessment, while X-rays remain critical for initial detection. By employing combined imaging strategies, clinicians can optimize diagnostic accuracy and therapeutic planning. This paper underscores the critical role of comprehensive radiological evaluation in managing osteogenic sarcoma in children
Osteogenic sarcoma is one of the most common malignant bone tumors in pediatric patients, necessitating early and accurate diagnosis to improve treatment outcomes. A multimodal radiological approach, integrating conventional radiography, MRI, CT, and PET scans, offers a comprehensive diagnostic pathway. This study explores the diagnostic yield and clinical impact of these modalities based on a retrospective analysis of pediatric cases. Findings reveal that MRI and PET provide superior sensitivity for local and metastatic assessment, while X-rays remain critical for initial detection. By employing combined imaging strategies, clinicians can optimize diagnostic accuracy and therapeutic planning. This paper underscores the critical role of comprehensive radiological evaluation in managing osteogenic sarcoma in children
| № | Author name | position | Name of organisation |
|---|---|---|---|
| 1 | Yusupalieva G.A. | Head of the Department of Medical Radiology | Tashkent State Medical University, |
| 2 | Shakirova L.M. | Assistant Lecturer | Tashkent State Medical University |
| № | Name of reference |
|---|---|
| 1 | 1.Ottaviani, G., & Jaffe, N. (2009). The epidemiology of osteosarcoma. Cancer Treatment and Research, 152, 3-13.2.Bielack, S. S., et al. (2002). Prognostic factors in high-grade osteosarcoma of the extremities or trunk: An analysis of 1,702 patients. Journal of Clinical Oncology, 20(3), 776-790.3.Costelloe, C. M., et al. (2009). Imaging in osteosarcoma. Journal of Clinical Oncology, 27(32), 5326-5331.4.Kaste, S. C. (2008). Imaging pediatric bone sarcomas. Radiologic Clinics, 46(3), 455-471.5.Iyer, R., et al. (2013). The diagnostic and prognostic value of MRI in osteosarcoma. Pediatric Radiology, 43(10), 1237–1245.6.Huang, J., et al. (2012). Roleof PET/CT in the staging and evaluation of treatment response in pediatric sarcomas. Pediatric Radiology, 42(10), 1180-1189.7.Eary, J. F., et al. (2011). Quantitative FDG PET in sarcoma patients: Metabolic response as a prognostic indicator. Radiology, 261(2), 511-520.8.Franzius, C., & Schober, O. (2006). Role of PET and PET/CT in the diagnosis and management of bone sarcomas. Eur J Nucl Med Mol Imaging, 33(10), 1125-1132.9.Weiss, J., et al. (2021). Advancements in multimodal imaging for pediatric oncology. Pediatric Blood & Cancer, 68(7), e28934.. |