This review focuses on the most important research topics that deal with issues that are currently being solved, those that remain unresolved, and future research directions. For the hepatitis A virus, we will address epidemiology, molecular surveillance, new susceptible populations, as well as environmental and food detections; for the hepatitis B virus, we will discuss host factors related to disease, diagnosis, therapy, and vaccine. Viral hepatitis, which is caused by infection with the hepatitis A, B, C, D, and E viruses, is a significant public health issue and a substantial cause of morbidity and mortality. As for the hepatitis D virus, we describe diagnostic methodology, pathogenesis, and therapy; for the hepatitis E virus, we will discuss epidemiology (including new emerging species), diagnosis, clinical aspects, treatment, vaccine development, and environmental surveillance; and for the hepatitis C virus, we will concentrate on pathogenesis, immunological response, direct action antiviral treatment in the context of solid organ transplantation, problems associated with the development of hepatocellular carcinoma, direct action antiviral resistance due to selection of resistance-associated variants and vaccination. The aforementioned underscores novel issues pertaining to hepatitis E globally,indicating the necessity for additional epidemiological, clinical, and virological research to better comprehend the various HAV, HBV, HCV HDV and HEV scenarios and effects globally
This review focuses on the most important research topics that deal with issues that are currently being solved, those that remain unresolved, and future research directions. For the hepatitis A virus, we will address epidemiology, molecular surveillance, new susceptible populations, as well as environmental and food detections; for the hepatitis B virus, we will discuss host factors related to disease, diagnosis, therapy, and vaccine. Viral hepatitis, which is caused by infection with the hepatitis A, B, C, D, and E viruses, is a significant public health issue and a substantial cause of morbidity and mortality. As for the hepatitis D virus, we describe diagnostic methodology, pathogenesis, and therapy; for the hepatitis E virus, we will discuss epidemiology (including new emerging species), diagnosis, clinical aspects, treatment, vaccine development, and environmental surveillance; and for the hepatitis C virus, we will concentrate on pathogenesis, immunological response, direct action antiviral treatment in the context of solid organ transplantation, problems associated with the development of hepatocellular carcinoma, direct action antiviral resistance due to selection of resistance-associated variants and vaccination. The aforementioned underscores novel issues pertaining to hepatitis E globally,indicating the necessity for additional epidemiological, clinical, and virological research to better comprehend the various HAV, HBV, HCV HDV and HEV scenarios and effects globally
| № | Имя автора | Должность | Наименование организации |
|---|---|---|---|
| 1 | Fayzullaeva Z.R. | Head teacher | Tashkent Medical Academy |
| 2 | Agzamova A.O. | student | Tashkent Medical Academy |
| 3 | Bekjanova J.U. | student | Tashkent Medical Academy |
| № | Название ссылки |
|---|---|
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Study the antifibrous efficacy ofplant proanthocyanidin in rats with chronic heliotrine liver damage. Frontline Medical Sciences and Pharmaceutical Journal, 2(05), 16–25. https://doi.org/10.37547/medical-fmspj-02-05-03.5.Aripov A.N., Aripov O.A., Akhundjanova L.L., Nabiev A.U., Nabieva D.A., & Khamroev T.T. (2022). Study the effect of yantacin on some indicators of cellular renewal and on the level of protein expression on rat hepatocytes in chronic heliotrine liver damage. International Journal of Medical Sciences And Clinical Research, 2(05), 06–13. https://doi.org/10.37547/ijmscr/Volume02Issue05-02.6.Арипов А.Н., Арипов О.А., Ахунджанова Л.Л., Набиев А.Ў., Нишанбаев С.З., Набиева Д.А., Ахмедова Д.И., Ҳамроев Т.Т. Сафорофлавонозиднинг сурункали токсик гепатит фонида жигарнинг асосий функцияларига таъсирини ўрганиш. Mutafakkir илмий журнал 2022 й, No 2, 37 –43.7.Арипов А.Н. Арипов О.А. Ахунджанова Л.Л. Набиева Д.А. Набиев А.Ў. Ахмедова Д.И. ҲамроевТ.Т. Современные методические приемы по выделению митохондрий из ткани печени при хроническим гкпатите у крыс и действия биологически активных веществ, выделенных из растений. “Zamonaviy ta’limning yutuqlari” mavzusidagi respublika ilmiy jurnali materiallari to’plami, 15 iyun 2022 yil. –Toshkent: «Sciences» MChJ, 2022. 16-26 бет.8.A.N. Aripov, O.A. Aripov, L.L. Akhunjanova, A.O’. Nabiev, B.B. Muhammadjonov, Karimov Sh.B., & Khamroev T.T. (2022). Problems and relevance of early diagnosis and treatment of severe hereditary and acquired diseases in children. Frontline Medical Sciences and PharmaceuticalJournal, 2(07), 6–15. https://doi.org/10.37547/medical-fmspj-02-07-029.Aripov A. N., Aripov O. A., Akhunjanova L. L., Nabiev A. O., Karimov Sh. B., Muhammadjonov B. B., & Khamroev T. T. (2022). Achievements and prospects in the diagnosis and treatment of hepatitis, current problems of viral etiology of hepatitis in children. American Journal of Interdisciplinary Research and Development, 7, 117–124. Retrieved from https://ajird.journalspark.org/index.php/ajird/article/view/21210.Aripov A. N, Akhunzhanova L. L, Nabiev A. U, Aripov A. O, Khamroev T. T.. Antifibrotic Efficacy of a New Phytocomposition of Essential Phospholipids with Glycyrrhizic Acid, Ecdysterone, Lycopene and Proanthacyanidin in Experimental Severe Chronic Hepatitis Compared with Phosphogliv. Biomed Pharmacol J 2023;16(3).Pages : 1815-1825. DOI : https://dx.doi.org/10.13005/bpj/2761 (Scopus)11.Aripov A. N, Akhunzhanova L. L, Nabiev A. U, Aripov O. A, Khamroev T. T. Evaluation of Antifibrotic Activity of a Combination of a New Phytocomposition and Proanthocyanidins in Rats.Biomed Pharmacol J 2024;17(4).12.Fayzullaeva Z. R., Yodgorova N. Bacteriological Methods Determination of the Respiratory Way in Chronic Infection //Eurasian Medical Research Periodical. –2022. –Т. 15. –С. 47-50. 13.Sadullaeva S., Fayzullaeva Z., Nazirova D. Numerical Analysis of Doubly Nonlinear Reaction-Diffusion System with Distributed Parameters //2020 4th International Symposium on Multidisciplinary Studies and Innovative Technologies (ISMSIT). –IEEE, 2020. –С. 1-3. 14.Файзуллаева З. Р. Иммунологические аспекты сахарного диабета при гнойновоспалительном заболевании: научное издание //Инфекция, иммунитет и фармакология. 2004; 1. –2004. –Т. 158.15.Файзуллаева З. Р. ФШ Маматмусаева Онкоген вирусларнинг хусусиятлари вестник тма2022,сони 10, 43-46http//repository. tma. uz/xmlui/handle/1/5642. –1990.16.Маматмусаева Ф. Ш. и др. Микроскопическая диагностика состава желчи у детей при вирусных гепатитах. –2023. 17.ФайзуллаеваЗ. и др. Фармакологические и микробиологические аспекты комплексного соединения никеля с пиридоксином и амидом никотиновой кислоты //Современные проблемы науки и образования. –2016. –No. 2. –С. 4-4.18.Файзуллаева, З. Р., & Эгамбердиева, А. Р. (2022). Сравнительная оценка дисбактериоз кишечника у беременных женщин. 19.Soatova MS, Karimova II, & Fayzullaeva ZR. (2021). Changes in the mouth microbiocionosis of 5-6 year old children with dental caries. Archive of Conferences, 23(1), 243-248. Retrieved from https://conferencepublication.com/index.php/aoc/article/view/104220.ХасанЮсуфУглиКаюмов, ЗамираРахматовнаФайзуллаева, УгилойСирочКизиСафарова, ГулсараБаходирКизиАхмедова, ЖахонгирНигматовичАсатуллаев. Противомикробная активность экстракта дикорастущего лекарственного растения.Portulaca oleracea L. // Universum: химия и биология : электрон. научн. журн. Каюмов Х.Ю. [и др.]. 2020. 12(78).21.Yodgorova N. T., Fayzullaeva Z. R., Sh M. F. Changes in the intestinal microflora in the baby and the ways of their correction //World Bulletin of Public Health. –2022. –Т. 17. –С. 37-41. 22.ТахирТухтаевичАдилбеков, ЗулайхоАлимжоновнаМаматова, ЗамираРахматовнаФайзулаева, СайёраСаъдуллаевнаШукурова, ФерузаШоназаровнаТухтаева. Влияние физической нагрузки на систему" двигательное окончание-мышечное волокно" Молодой ученый, 2020, 9, 75-77. URL: https://7universum.com/ru/nature/archive/item/1099523.Tuychiev, L. N., Nuruzova, Z. A., Mamatmusayeva, F. S., Yodgorova, N. T., & Fayzullayeva, Z. R. (2021). Microscopic composition of bile in children with convalescents of viral hepatitis" A" and" C". 24.Fayzullaeva , Z. . (2023). Homiladorlik davrida mikrofloraning oʻzgarishi va uni yaxshilashning ahamiyati. Центральноазиатский журнал академических исследований, 1(2), 5–10. извлечено от https://www.in-academy.uz/index.php/cajar/article/view/2351825.Mamatmusaeva, F. S., Nuruzova, Z. A., Aliev, S. R., Fayzullaeva, Z. R., & Yodgorova, N. T. (2023). Microscopic composition of bile in convalescent of viral hepatitis" A"," B" and" C" of children. Onomázein, (62 (2023): December), 1284-1295.26.Fayzullayeva, Z., Akbar , A., & Abdusattarov, A. (2024). Dempfirlash hadiga, o‘zgaruvchan zichlikka ega diffuziya jarayonlarini modellashtirish: Dempfirlash hadiga, o‘zgaruvchan zichlikka ega diffuziya jarayonlarini modellashtirish. Modern problems and prospects of applied mathematics, 1(01). Retrieved from https://ojs.qarshidu.uz/index.php/mp/article/view/433 |