Hyperbilirubinemia in newborns is a complex clinical and biochemical syndrome caused by multifactorial disorders of bilirubin metabolism in the early postnatal period. The modern understanding of the pathophysiology of this condition is based on the integration of fundamental knowledge about the molecular and cellular mechanisms of formation, transport, conjugation, and elimination of bilirubin
Hyperbilirubinemia in newborns is a complex clinical and biochemical syndrome caused by multifactorial disorders of bilirubin metabolism in the early postnatal period. The modern understanding of the pathophysiology of this condition is based on the integration of fundamental knowledge about the molecular and cellular mechanisms of formation, transport, conjugation, and elimination of bilirubin
| № | Имя автора | Должность | Наименование организации |
|---|---|---|---|
| 1 | Samiyeva S.U. | Resident Physician | Children's Multidisciplinary Medical Center of Samarkand Region |
| 2 | Olimjonova F.. | student | Samarkand State Medical University |
| 3 | Olimjonova Z.. | student | Samarkand State Medical University |
| № | Название ссылки |
|---|---|
| 1 | 1.Watchko JF, TiribelliC. Bilirubin-induced neurologic damage -mechanisms and management approaches. N Engl J Med. 2023;369(21):2021-2030.2.Bhutani VK, Wong RJ. Bilirubin-induced neurologic dysfunction (BIND). Semin Fetal Neonatal Med. 2022;28(2):101291.3.Maisels MJ, McDonagh AF. Phototherapy for neonatal jaundice. N Engl J Med. 2022;358(9):920-928.4.Kaplan M, Bromiker R, Hammerman C. Hyperbilirubinemia, hemolysis, and increased bilirubin neurotoxicity. Semin Perinatol. 2023;38(7):429-437.5.Blackburn S. Hyperbilirubinemia and neonatal jaundice. Neonatal Netw. 2022;14(7):15-25.6.Olusanya BO, Kaplan M, Hansen TWR. Neonatal hyperbilirubinaemia: a global perspective. Lancet Child Adolesc Health. 2023;2(8):610-620.7.Nakamura H, Yonetani M, Uetani Y, et al. Determination of serum unbound bilirubin for prediction of kernicterus in low birthweight infants. Acta Paediatr Jpn. 2022;34(6):642-647.8.Raimondi F, Crivaro V, Capasso L, et al. Unconjugated bilirubin modulates the intestinal epithelial barrier function in a human-derived in vitro model.Pediatr Res. 2023;79(2):394-400. |